What Are the Key Differences Between Delta-8 and Delta-10 THC?

Feb 1 / Jenifer Marks, Esq.

Delta-8 THC and Delta-10 THC are two of the most popular emerging cannabinoids in the cannabis industry today. Both are derived from hemp, federally legal, and offer psychoactive effects—but their experiences and benefits are distinct.

As consumer demand grows, it’s essential to understand how these compounds differ and how to choose the right product for your recreational or medical marijuana needs.

If you are interested in learning about how medical cannabis helps the body, take this FREE Medical Cannabis Class.

Delta-8 THC and Delta-10 THC are minor cannabinoids naturally present in cannabis and hemp plants. Unlike Delta-9 THC (the primary psychoactive compound in marijuana), these cannabinoids occur in trace amounts and are typically produced through a chemical process called isomerization from hemp-derived CBD.

Delta-8 THC: Known for its mellow, relaxing effects. Users often describe it as a smoother, less intense version of Delta-9 THC, making it perfect for relaxation and nighttime use.
Delta-10 THC: Offers a more energizing and uplifting experience. Consumers report a gentle mental buzz ideal for creativity, focus, and daytime activities.

Though Delta-8, Delta-10, and Delta-9 THC share similar chemical compositions, the position of their double carbon bond differs:

Delta-8 THC: Bond appears on the 8th carbon chain.
Delta-10 THC: Bond appears on the 10th carbon chain.
Delta-9 THC: Bond appears on the 9th carbon chain.

These structural variations affect how each cannabinoid interacts with the body’s endocannabinoid system (ECS), resulting in distinct psychoactive effects. To learn more about the ECS take our FREE Medical Cannabis Class!

Delta-8 THC: Approximately 50% as potent as Delta-9 THC, known for delivering a calm, clear-headed high with reduced chances of anxiety or paranoia.
Delta-10 THC: Estimated to be 20-30% less potent than Delta-8, producing mild energizing effects suitable for daytime use without overstimulation.

Under the 2018 Farm Bill, hemp-derived cannabinoids with less than 0.3% Delta-9 THC are federally legal in the U.S. However, individual states can impose restrictions. Always check local laws before purchasing these products.

Here is a side-by-side comparison of Delta-8 and Delta-10:

Since both cannabinoids appear in minimal amounts in hemp plants, they are typically synthesized from hemp-derived CBD through a process called isomerization.

Extraction Process:

1. Extract CBD from hemp.

2. Convert the CBD to Delta-8 or Delta-10 using safe chemical reactions.

3. Purge residual solvents to ensure safety.

Note: Only purchase products from brands that provide a Certificate of Analysis (COA) to verify purity and potency.

Consumers can find a variety of Delta-8 and Delta-10 THC products, including:

Flower
Vape cartridges
Tinctures and oils
Edibles (gummies, chocolates)
Beverages
Concentrates

Yes. Standard drug tests detect THC metabolites, which means using either Delta-8 or Delta-10 can trigger a positive result, just like traditional Delta-9 THC.

The FDA has not approved Delta-8 or Delta-10 THC for medical use, and concerns exist regarding:

Inaccurate labeling and potency claims
Contamination from unsafe chemicals used during manufacturing
Potential health risks, especially in children and pets

Be cautious of products that lack third-party testing or COAs.