Mango and cannabis have a surprising synergy that goes beyond flavor. There’s a growing belief, supported by some scientific evidence, that eating mangoes before consuming cannabis can intensify and extend the effects of a cannabis high. But what’s the science behind this? The answer lies in myrcene, a terpene found in both mangoes and cannabis.

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When you consume cannabis, THC enters the bloodstream and interacts with receptors in the brain. Myrcene, a dominant terpene in both mangoes and certain cannabis strains, may amplify this effect. A study published on NCBI highlights myrcene's sedative and pain-relieving properties, which may contribute to its ability to deepen the effects of THC. When myrcene levels in the body are elevated by eating mangoes, it’s thought to help THC cross the blood-brain barrier more efficiently, enhancing and prolonging the high.

Myrcene doesn’t just contribute to a fruity aroma—it plays a crucial role in the entourage effect, where terpenes and cannabinoids work together to enhance each other's effects. This phenomenon is a fundamental part of cannabis therapeutics, where compounds like THC and CBD interact with terpenes to produce specific effects. The University of Arizona Health Sciences Study shows that certain Cannabis sativa terpenes, including myrcene, can be as effective as prescription drugs for pain relief, highlighting the powerful potential of terpenes in cannabis therapy.

The form in which you consume mangoes can impact how well myrcene works with cannabis. Raw mangoes are recommended, as cooking may reduce the terpene content. If you prefer variety, try blending frozen mango into a smoothie, which maintains the fruit’s natural myrcene levels.

In addition to enhancing the high, mangoes are also a great option when the munchies hit. They’re low in calories, high in water, and packed with fiber, making them a healthier alternative to typical munchie snacks like chips and cookies. Plus, mangoes' natural sugars and fiber can help stabilize blood sugar levels.

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For cannabis enthusiasts, understanding the science behind mangoes and cannabis can offer a natural way to optimize the cannabis experience. The powerful combination of myrcene and THC showcases the potential of the entourage effect, where the interplay between terpenes and cannabinoids can amplify therapeutic and recreational benefits.